Quantitative Risk Analysis for Quantal Reproductive and Developmental Effects
نویسندگان
چکیده
منابع مشابه
Quantitative risk analysis for quantal reproductive and developmental effects.
Animal experiments are generally conducted at higher dose levels than anticipated human dose levels in order to elicit otherwise subtle changes in reproduction or developmental effects with relatively few animals. Based on animal data, regulatory strategy generally has been to postulate a no-observed-effect level (NOEL) for toxic effects and to divide this by a safety factor, usually 100, to es...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1989
ISSN: 0091-6765
DOI: 10.2307/3430557